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Production in insect cells

Our team offers expert guidance and tailored services to define the most relevant strategy for your protein production in the Baculovirus-insect cells expression system.

GTP Bioways CDMO - CMC Development

Unique expertise in protein expression in insect cells

The popularity of the insect cell-baculovirus expression system lies in its ability to produce relatively large quantities of post-translationally modified eukaryotic proteins at competitive costs.

Since the system is lytic, it is suited for both intracellular and secreted proteins, and is ideal for proteins with inhibitory or toxic effects on the cell host.

At GTP Bioways, we have extensively used insect cells to efficiently produce a variety of proteins, including enzymes, receptors and blood factors.

We are confirmed experts in protein production

with insect cells and have successfully produced proteins used as targets for therapeutics development, as reagents for diagnostic and analytical assays and for vaccine development programmes.

Cell line Development process

Comprehensive services for successful protein production in baculovirus-insect cells

To help you on your way to successful production in insect cells, GTP Bioways offers a comprehensive range of services including:

    • Generation of recombinant baculovirus and virus stock preparation
    • Optimisation of cell culture critical parameters, such as insect cell line, MOI, kinetic of expression
    • Development/optimisation of the purification process
    • Scale-up of production up to 50L culture

GTP Bioways has expertise with other expression systems

We excel at protein production with all prominent industrial microbial, mammalian and insect cell expression systems such as P. pastoris, CHO, HEK and Sf9.

E. coli

We have successfully developed protein expression processes in E. coli with a diversity of strategies.

Yeast

Our team has strong experience with various recognised P. pastoris expression systems.

Mammalian cells

We are experts in the production of target, reagent and vaccine proteins using insect cells.